List Of Hazardous Chemicals In Smokeless Tobacco Is Expanded In New Study

Attention all smokeless tobacco users: It's time to banish the comforting notion that snuff and chewing tobacco are safe because they don't burn and produce inhalable smoke like cigarettes. A study that looked beyond the well-researched tobacco hazards, nitrosamines and nicotine, has discovered a single pinch –– the amount in a portion –– of smokeless tobacco exposes the user to the same amount of another group of dangerous chemicals as the smoke of five cigarettes.The research on polycyclic aromatic hydrocarbons (PAH) in smokeless tobacco was reported at the 238th National Meeting of the American Chemical Society (ACS). It adds to existing evidence that smokeless contains two dozen other carcinogens that cause oral and pancreatic cancers, the scientists say.

"This study once again clearly shows us that smokeless tobacco is not safe," said Irina Stepanov, Ph.D., who led the research team. "Our finding places snuff on the same list of major sources of exposure to polycyclic aromatic hydrocarbons as smoking cigarettes." PAHs are widespread environmental contaminants formed as a result of incomplete burning of wood, coal, fat in meat, and organic matter. PAHs form, for instance, during the grilling of burgers, steaks and other meat.

The findings come in the midst of a rise in both marketing and consumption of smokeless tobacco, which many consumers regard as less dangerous than other forms of tobacco. Estimates suggest that sales of moist snuff in the United States have doubled since the 1980s.

"The feeling of safety among some smokeless users is wrong," said Stepanov, a chemist with Masonic Cancer Center, University of Minnesota, Minneapolis. "A total of 28 carcinogens were identified in smokeless tobacco even before our study. Continued exposure to these over a period of time can lead to cancer. Now we have found even more carcinogens in snuff." In addition to the heightened cancer risk, she noted that chronic use of snuff leads to nicotine addiction, just as it does with cigarette smoking.

Stepanov said that until recently, scientists believed that only trace amounts of PAH existed in snuff because the tobacco was not burned when used. This assumption proved to be wrong. "Even though smokeless tobacco use does not involve burning, moist snuff is getting contaminated with PAH during its manufacturing," according to Stepanov. The most likely source of this contamination with PAH is the curing process that is used to turn tobacco leaves into snuff. This process is called 'fire-curing', and it puts tobacco into direct contact with the smoke generated by smoldering hardwoods –– a rich source of various PAHs.

Looking to the next project, she said the team is working on a study that will examine a wide range of smokeless tobacco brands to compare PAH levels among them.

Funding for Stepanov's research came from the National Cancer Institute and the National Institute on Drug Abuse to the Transdisciplinary Tobacco Use Research Center at the University of Minnesota. The research team working on this project includes Dr. Dorothy Hatsukami and Dr. Stephen Hecht, renowned experts in tobacco carcinogenesis and tobacco harm reduction.

Links Between Video-game Playing And Health Risks In Adults Found

While video gaming is generally perceived as a pastime for children and young adults, research shows that the average age of players in the United States is 35. Investigators from the Centers for Disease Control and Prevention (CDC), Emory University and Andrews University analyzed survey data from over 500 adults ranging in age from 19 to 90 in the Seattle-Tacoma area on health risks; media use behaviors and perceptions, including those related to video-game playing; and demographic factors. In an article published in the October 2009 issue of the American Journal of Preventive Medicine, they found measurable correlations between video-game playing and health risks.Participants reported whether they were players or nonplayers, and weekly usage was collected. Internet usage was assessed, as was the relative importance of the Internet as a social support. The personal determinants examined in this study included self-assessments of depression, personality, health status, physical and mental health, body mass index (BMI), and poor quality of life. Immersion in media environments was evaluated using the participants' estimates of the time they spent during a typical week surfing the Internet and watching TV, including videos and DVDs. The Seattle–Tacoma area was selected because of its size (13th largest US media market) and its Internet usage level is the highest in the nation.

A total of 45.1% of respondents reported playing video games. Female video-game players reported greater depression and lower health status than female nonplayers. Male video-game players reported higher BMI and more Internet use time than male nonplayers. The only determinant common to both female and male video-game players was greater reliance on the Internet for social support.

Writing in the article, Dr. James B Weaver III, PhD, MPH, National Center for Health Marketing, CDC, Atlanta, states, "As hypothesized, health-risk factors – specifically, a higher BMI and a greater number of poor mental-health days – differentiated adult video-game players from nonplayers. Video-game players also reported lower extraversion, consistent with research on adolescents that linked video-game playing to a sedentary lifestyle and overweight status, and to mental-health concerns. Internet community support and time spent online distinguished adult video-game players from nonplayers, a finding consistent with prior research pointing to the willingness of adult video-game enthusiasts to sacrifice real-world social activities to play video games. The data illustrate the need for further research among adults to clarify how to use digital opportunities more effectively to promote health and prevent disease."

In a commentary in the same issue, Brian A. Primack, MD, EdM, MS, from the University of Pittsburgh School of Medicine, applauds Weaver et al. for focusing on the current popularity of video games not only among youth, but also among adults. He suggests that many video games are different enough from original forms of play that they may be better defined as "playlike activities." He writes, "There are noteworthy differences between the oldest forms of play (e.g., chase games) and today's 'playlike activities.' These playlike activities may stimulate the right centers of the brain to be engaging ... However, the differences between today's 'playlike activities' and original forms of play may illuminate some of the observed health-related correlates discovered by Weaver, et al."

Dr. Primack observes that our greatest challenge will be maintaining the balance: "How do we simultaneously help the public steer away from imitation playlike activities, harness the potentially positive aspects of video games, and keep in perspective the overall place of video games in our society? There are massive, powerful industries promoting many playlike activities. And industry giants that can afford to will successfully tout the potential benefits of health-related products they develop. But who will be left to remind us that – for children and adults alike – Hide-And-Seek and Freeze Tag are still probably what we need most?"

The article is "Health-Risk Correlates of Video-Game Playing Among Adults" by James B Weaver III, PhD MPH; Darren Mays, MPH; Stephanie S Weaver, PhD, MPH; Wendi Kannenberg, MPH; Gary L Hopkins, MD DrPH; Dogan Eroglu, PhD; and Jay M Bernhardt, PhD MPH. The commentary is "Video Games: Play or 'Playlike Activity'?" by Brian A Primack, MD, EdM, MS. Both appear in the American Journal of Preventive Medicine, Volume 37, Issue 4 (October 2009) published by Elsevier.